A Curtis Davies own goal gifted West Ham United a point after Hull City had twice taken the lead in a frenetic 2-2 draw in the Premier League on Monday.
Champions Manchester United will travel to Swansea City for their first English Premier League match under new manager David Moyes, while Manuel Pellegrini's Manchester City are at home to Newcastle United on August 17.
Arsenal's new manager Unai Emery faces a baptism of fire after the Gunners were handed an opening day fixture at home to Premier League champions Manchester City.
Juventus's new signing Sami Khedira will miss the first two months of the season with a thigh injury, the Serie A champions said.
When Alex Ferguson finally called time on his career, he stood on the Old Trafford pitch and invited Manchester United fans to support his successor by remembering the dark times as well as the good.
Images from Saturday's Premier League action.
Real Madrid's French duo Karim Benzema and Ferland Mendy struck in the second half as the Spanish champions overcame an injury crisis to beat Getafe 2-0 at home on Tuesday and close the gap to La Liga leaders Atletico Madrid to five points.
The champions beat Aston Villa 2-1 while Manchester United went down 1-2 at home to Blackburn Rovers in the Premier League.
Chelsea reached the League Cup quarter-finals thanks to two own goals in a 3-2 win over second-tier Derby County on Wednesday as Frank Lampard's return to his former club ended in disappointment.
Liverpool's Slot not nervous ahead of Anfield debut
Leandro Trossard transformed the mood at Arsenal with the winning goal as they recovered from an early setback to beat Tottenham Hotspur 2-1 at home.
Table toppers Chelsea have seen their lead reduced to just six points thanks to a revival from reigning champions Manchester City. If Chelsea slip, City can pile on the pressure to make the EPL battle a little interesting.
Chelsea striker Demba Ba struck twice on his debut as the FA Cup holders enjoyed a 5-1 drubbing of Southampton in the third round on Saturday and Robin van Persie's majestic last-gasp equaliser salvaged a 2-2 draw for Manchester United at West Ham.
Leaders Chelsea have seen their lead reduced to just three points after a shock defeat, and a revival from defending champions Manchester City. Manchester United are back in third after a run of five straight wins. If Chelsea slip agains, City continue to pile on the pressure and United keep the winning momentum it will make EPL battle further interesting.
Trinidad & Tobago goalkeeper Shaka Hislop said he could die happy after keeping Sweden at bay in a shock 0-0 World Cup draw.
Holders and Premier League leaders Arsenal will be at home to Championship (second tier) Burnley in the fourth round of the FA Cup after most of the big guns avoided top flight opponents in Monday's draw.
Images from the English Premier League matches played on Saturday
United are four points behind fourth-placed Arsenal, with a game in hand, as they search for a way into the top four and a place in next season's Champions League.
Fulham's home game against Brighton & Hove Albion on Wednesday has also been pushed behind closed doors, while West Ham United too will host Crystal Palace without spectators on the same day.
Four months after quitting Liverpool for Manchester City, Raheem Sterling will have the first opportunity to justify the move by getting one over his former employers when the teams meet at the Etihad Stadium on Saturday.
Arsenal's Germany international Mesut Ozil will be out for up to three matches with a shoulder injury, manager Arsene Wenger said on Sunday.
Match-by-match facts and statistics ahead of the Premier League
Three matches into the Premier League season following a stunning title success by 5,000-1 outsiders LeicesterCity, the table already has a more familiar look.
News of all that's transpired on and off the football field
News of all that transpired on and off the football field.
With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
Chelsea midfielder Frank Lampard and defender Branislav Ivanovic will be out of action until the end of January, the Chelsea website reported on Wednesday.
Luton pulled one back on the half-hour mark when Chelsea keeper Kepa Arrizabalaga failed to keep out Jordan Clark's low effort which squeezed between his hand and leg into the net.
Images from the English Premier League matches played on Saturday.
Arsenal laboured to their second win of the season with a highly-charged 1-0 victory against 10-man Newcastle United at St James' Park on Saturday.
Liverpool strolled to a 2-0 victory over Brentford, while Newcastle drew 1-1 at Bournemouth.
Chelsea lost for the sixth time in six games in all competitions since interim coach Frank Lampard replaced Graham Potter last month, a dismal run for a club who were crowned European champions as recently as two years ago.
Images from the English Premier League matches played on Saturday
Following is a match by match look at the English Premier League's weekend fixtures:
Images from EPL matches played on Tuesday
'Jose Mourinho has been charged with misconduct in relation to his language and/or behaviour towards the match officials in or around the dressing room area at halftime'
Louis van Gaal came under fresh attack on Friday over his style of play at Manchester United and acknowledged he was still struggling to come up with a preferred system.
Manchester City manager Pep Guardiola has been named the Premier League manager of the month for February, while in-form Tottenham Hotspur striker Harry Kane picked up his fourth player of the month award.
Promoted Bournemouth are still waiting for their first Premier League points after succumbing to a controversial Christian Benteke goal in a 1-0 defeat at Liverpool on Monday.
Barcelona were held to a 0-0 home draw by Galatasaray in the first leg of their Europa League last-16 tie